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28 SMILES: CC(=O)OC1=C(Cl)C=C2C(OC3=CC(OC(C)=O)=C(Cl)C=C3C22OC(=O)C3=CC(=CC=C23)C(O)=O)=C1
Product Name Val-Ala-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C33H58N4O12 Molecular Weight 702
Product Name Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C86H139N13O25 Molecular Weight 1755
The good spectroscopic properties
Product Name Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C85H133N15O24 Molecular Weight 1749
Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP Size:25mg 28 SMILES: CC(=O)OC1=C(Cl)C=C2C(OC3=CC(OC(C)=O)=C(Cl)C=C3C22OC(=O)C3=CC(=CC=C23)C(O)=O)=C1SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The
